Healthy Aging/Longevity

Aeon Longevity Formula is a unique blend of research backed ingredients including: -Spermidine-Ca-AKG-Dihydroberberine-Tetrahydrocurcumin-L-Ergothioneine-... and more This combination was designed to mitigate aging and rejuvenate the body all the way down to the cellular level.* Spermidine 3 mg Cellular Support: Results from preclinical studies indicate spermidine supports DNA Stability, cellular growth, and apoptosis. (1) Longevity Enhancement: Results from preclinical studies indicate higher consumption of spermidine-rich foods correlates with reduced mortality and a life expectancy prolonged by 5 years. (1) Neurological Support: Results from preclinical studies indicate spermidine assists in the removal of toxic protein aggregates in cells; the cause of dementia and diseases like Parkinson's and Alzheimer's. (1) KEY BENEFITS: Replenishes depleted levels of Spermidine to inform youthful aging, and increases cellular health and immune system.* Ca-AKG ( Calcium Alpha-Ketoglutarate Monohydrate) 1000 mg Antioxidant Support: Results from preclinical studies indicate that Ca-AKG protects against free radical damage related to aging processes and improves blood vessel elasticity in aging organisms. (7) Longevity Enhancement: Results from preclinical studies indicate Ca-AKG increases the health span of mice by 41% and reduces 31 different signs of age-related frailty.(8) KEY BENEFITS: Decreases inflammation, increases cellular energy, improves training volume and power output in exercise, increases health span, improves bio-markers of aging.* MitoPrime™ (L-Ergothioneine) 10 mg Superior Antioxidant Activity: Results from preclinical studies indicate that supplemental L-ergothioneine is up to 30x better than glutathione, and significantly outperforms CoQ10 and Vitamin C. (12) Oxidative Stress Reduction: Results from preclinical studies indicate that supplemental L-ergothioneine can reduce oxidative stress, which protects mitochondrial function and DNA, and in turn protects against aging. (13) Restorative:  Results from preclinical studies indicate that supplemental L-ergothioneine can increase natural  stores, which decline after age 18. Low levels are associated with suboptimal performance. (14) KEY BENEFITS: Improves cognitive function, and immune health. Diminishes oxidative stress and accelerates exercise recovery.* GlucoVantage ® (Dihydroberberine) 200 mg Improved Bioavailability: Results from preclinical studies indicate that DHBBR is 5x more bioavailable/absorbable than berberine + 2x longer lasting than berberine, 8 hours vs. 4 hours. (2) AMPk Activation: Results from preclinical studies indicate that DHBBR supports body composition goals via AMPK, improving insulin sensitivity and carbohydrate tolerance (3) Longevity Enhancement: Results from preclinical studies indicate that DHBBR reduces glycation end-products. (4) KEY BENEFITS: Activates AMPK, controls blood glucose levels, increases insulin sensitivity and fat oxidation. It may also help facilitate the ketogenic state.* Curcuprime ™ (Tetrahydrocurcumin) 200 mg Cognitive Support: Results from preclinical studies indicate that tetrahydrocurcumin supports cognitive function via acetylcholine protection. (5) Histamine Support: Results from preclinical studies indicate that tetrahydrocurcumin improves histamine response associated with alertness. (6) Powerful antioxidant properties: Results from preclinical studies indicate tetrahydrocurcumin supports healthy inflammatory response. (6) Metabolism: Results from preclinical studies indicate tetrahydrocurcumin improves insulin sensitivity, reduces serum and liver cholesterol, triglycerides, and free fatty acids. (6) KEY BENEFITS: Improved cognitive function and insulin sensitivity, decreases inflammation and reduces cholesterol values.* Learn more: Tetrahydrocurcumin(Curcuprime™) Spermidine Ca-AKG(Calcium Alpha-Ketoglutarate Monohydrate) GlucoVantage ®(Dihydroberberine)  

Our AMPk Activator formula, formerly "Dihydroberberine", features a highly bioavailable form of dihydroberberine: GlucoVantage®, which has been shown to be up to 5x more bioavailable and 2x longer lasting than regular berberine. AMPk Activator is ideal for men and women who want an effective nutritional therapy for glucose balance, lipid metabolism and cardiovascular health that is both well-tolerated and convenient.*  Deeper Look: Dihydroberberine is a metabolite of berberine which bypasses the rate-limiting step of microbial reduction, ensuring greater functional benefits over berberine.[7],[8] Berberine has been shown to directly interact with adenosine mono-phosphate kinase (AMPK), a protein that plays a key role in regulating energy balance.[2] AMPK activity is felt in various bodily processes, including those relevant to insulin sensitivity. In fact, berberine has been shown to increase AMPK activity, which can enhance insulin sensitivity.[3] Berberine supplementation has improved multiple markers of insulin sensitivity in research. Studies have found that the ingredient can lower blood glucose, hemoglobin, triglycerides, and cholesterol.[6] Berberine increases adiponectin,[4] a protein secreted by fat cells that influences insulin reception on a cellular level. Further research has found that this increase in adiponectin improves insulin sensitivity. [5] Results from pre-clinical studies indicate berberine promotes healthy endothelial function, an action attributed in part to its ability to reduce oxidative stress.[1] References

DHEA is a natural steroid hormone that is synthesized from cholesterol through pregnenelone by the adrenal glands. DHEA acts as an antagonist for glucocorticosteroid hormones and is the parent precursor for other important steroid hormones, such as estradiol and other estrogens, and testosterone. While not a precursor to progesterone, DHEA can indirectly influence progesterone synthesis through a feedback mechanism whereby pregnenelone is converted to progesterone based on DHEA levels. DHEA levels drop approximately 10% per decade after age 25.  *Please see the DHEA International Shipping information, regarding countries that do NOT allow import of DHEA. Please check the list prior to placing your order, if you are outside of the U.S.

MitoQ is a ground-breaking product which supports youthful energy levels and can reduce the free radical damage which contributes to many of the symptoms of aging and various health problems.  With its unique action, MitoQ supports the health of the trillions of cells in your body like nothing else can. MitoQ protects your cells from damaging free radicals ensuring they stay healthy and full of energy. MitoQ is absorbed throughout your body, recharging your cells from head to toe.  How does MitoQ work? Inside each of our cells are huge numbers of tiny, energy-producing power plants called “mitochondria”. Mitochondria convert the food we eat and the air we breathe into the energy that powers our cells, and in turn, us. When mitochondria produce this energy, they also produce damaging by-products known as free radicals. Luckily our mitochondria and cells are packed with antioxidants which can neutralize free radicals before they can do too much damage. However, as we age, or when we are unwell, our antioxidant supply diminishes and the free radicals start to take an ever-increasing toll on our cells. MitoQ is a true breakthrough as it is the only antioxidant which can effectively target and recharge our own cellular batteries, mitochondria. MitoQ neutralizes harmful free radicals at the source before they get the chance to get out and damage our cells. This means our cells can get on with their job of producing all the energy we need to keep us healthy and active. Learn more about MitoQ in this PDF - Product Brochure

Recent research has highlighted the potential benefits of NAC + Glycine, which combines N-acetylcysteine (NAC) and glycine, to include: Restoration of Health Gluathione Levels: Glutathione levels decline significantly with age, leading to increased oxidative stress and potentially contributing to various age-related health problems Improved Mitochondrial Function: NAC + Glycine supplementation has been shown to improve mitochondrial fatty acid oxidation and correct multiple aspects of mitochondrial dysfunction in older adults, including abnormalities in mitochondrial biogenesis, nutrient sensing, β-oxidation, electron transport chain function, ATP synthesis, and mitophagy Metabolic Health: Aging is also associated with the development of insulin resistance and metabolic dysfunction. NAC + Glycine supplementation has been shown to significantly improve insulin sensitivity and reduce insulin resistance in older adults, as measured by HOMA-IR Reduced Harmful Effects of Oxidative Stress: The ability of NAC + Glycine to improve glutathione status and reduce oxidative stress without inducing reductive stress is a key advantage over other antioxidant supplementation strategies In addition, a study from the Baylor College of Medicine suggests that the use of NAC + Glycine supplementation as a promising strategy for promoting healthy aging and improving multiple age-related health outcomes. By addressing key hallmarks of aging, such as glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, and physical decline, NAC + Glycine supplementation may help to prevent or mitigate various age-related diseases and extend healthspan.

Our bodies naturally produce high levels of Alpha-Ketoglutarate (AKG) until age 40. But after age 40, levels of AKG drastically drop. We all need AKG to live a healthy, longer life. And we can’t get enough of it by eating food. Rejuvant LifeTabs is a once-daily dietary supplement, containing the patent-pending ingredient, LifeAKG™. LifeAKG is a proprietary, sustained-release form of AKG which is safe, free of unwanted drug side effects, and scientifically shown to extend life.In a landmark longevity study, conducted by researchers at the prestigious Buck Institute for Research on Aging, Rejuvant’s LifeAKG was shown to increase lifespan at 12%, average between males and females. Just as importantly, the gold-standard study showed LifeAKG increased the healthspan, the healthiest years of life, by 41%, reducing 31 different signs of age-related frailty.