Healthy Aging/Longevity

Everyone knows their chronological age. Chronological age is the number of candles that are on top of your cake and the birthdays you celebrate(or sometimes don't). However, developments in science have created another measurement of age called biological or epigenetic age. Unlike chronological age, this measurement of age is based on years of statistical research and provides much more relevant health information, It can tell us how healthy you are and even when you might pass away.TruAge uses biomarkers on your DNA called methylation. All you have to do is send us a blood sample! (Sample Collection Instructions) **DunedinPACE (The first 3rd generation and probably best aging algorithm) and the telomere length reports now included! Your biological age is more accurate at predicting health span(how healthy you are) and life span(how long you will live) than any previous molecular biomarker, and can be correlated to almost any health factor such as physical fitness, socioeconomics status and drug use history. Ideally, everyone would want their biological age to be less than their chronological age. This means that you are living a lifestyle that is healthy and will help you stay free of sickness and disease longer! READ MORE: TruAge Test Info Sheet TruDiagnostic

As we age, our body's natural collagen production declines, leading to fine lines and wrinkles. Our marine collagen peptides work to replenish collagen levels, promoting stronger hair and nails, improved skin elasticity, and enhanced hydration for a radiant, youthful appearance. This versatile supplement also supports cartilage health and joint mobility, boosts gut health, and aids in muscle recovery and performance, helping you look, feel, and perform at your best every day.

TB4-Frag 500 is a fragment of a naturally occurring peptide called Thymosin Beta-4 (TB4) combined with salcaprozate sodium (SNAC) for enhanced absorption. Thymosin Beta-4 Frag(1-4) (Ac-SDKP) is a naturally occurring tetrapeptide from thymosin beta-4 that is made up of the amino acids Ac-Ser-Asp-Lys-Pro. It is a shorter fragment of the original peptide, which has been found to have better oral bioavailability and approximately 10 times more potent by weight compared to the full-length peptide. This is due to its smaller size and modified structure, which allows it to be more easily absorbed by the body when taken orally. Research underscores its regenerative properties, ability to modulate the immune system, address inflammaging, and its supportive roles in gut health, cardiovascular health and reducing kidney/liver fibrosis.* It may even inform a more natural approach for high blood pressure due to its association with angiotensin-converting enzyme.*  Salcaprozate sodium, or SNAC, is a cutting-edge ingredient created to promote intestinal permeation. It was originally developed for improving the oral delivery of macromolecules. Clinical research demonstrates SNAC's ability to significantly enhance absorption, increasing peptide uptake by up to nine times without disrupting the integrity of intestinal tight junctions.  This innovative approach supports optimal absorption for maximum effectiveness. Peptide Bioavailability Peptides are short chains of amino acids that are being extensively researched for their potential therapeutic benefits. While they are commonly associated with subcutaneous (SubQ) Administration, recent advancements in peptide modification have allowed for better oral bioavailability. In fact, many peptides can now be taken orally in pill or capsule form, making them more convenient and accessible to a wider range of research and clinical studies. Thymosin Beta 4 is a peptide with a wide range of potential therapeutic benefits. It has been shown to promote wound healing, reduce inflammation, and stimulate tissue repair in numerous animal studies. However, in its original form, TB4 had to be administration subcutaneously to be effective. Thymosin Beta4 Fragment SDKP is a modified form of TB4 and TB500 that has been shown to have better oral bioavailability, allowing it to be effective when taken orally rather than via SubQ administration. A study published in the Journal of Chromatography B demonstrated that Thymosin Beta4 Fragment SDKP had approximately 30% oral bioavailability in rats, which is significantly higher than the less than 1% bioavailability observed with TB500. Another study published in the Journal of Peptide Science showed that Thymosin Beta4 Fragment SDKP had a longer half-life and a greater area under the curve (AUC) than TB500 when taken orally in rats. These findings provide strong scientific evidence that modifications to peptide sequences, such as fragmenting longer sequences, can significantly improve their bioavailability and effectiveness when taken orally. The development of oral availability is an exciting advancement in the field of peptide therapeutics. While subQ administrations have been the primary mode of administration for many peptides, recent research has shown that modifying the salt form of a peptide like BPC-157, can improve its oral bioavailability, making it a viable alternative to injections. This offers numerous benefits, including greater convenience, reduced pain and discomfort, and improved compliance. With ongoing research and development, it is likely that we will continue to see progress in the field of orally available peptides, providing new treatment options