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Recent research has highlighted the potential benefits of NAC + Glycine, which combines N-acetylcysteine (NAC) and glycine, to include:
Restoration of Healthy Gluathione Levels:
Glutathione levels decline significantly with age, leading to increased oxidative stress and potentially contributing to various age-related health problems
Improved Mitochondrial Function:
NAC + Glycine supplementation has been shown to improve mitochondrial fatty acid oxidation and correct multiple aspects of mitochondrial dysfunction in older adults,
including abnormalities in mitochondrial biogenesis, nutrient sensing, β-oxidation, electron transport chain function, ATP synthesis, and mitophagy
Metabolic Health:
Aging is also associated with the development of insulin resistance and metabolic dysfunction. NAC + Glycine supplementation has been shown to significantly improve insulin sensitivity and reduce insulin resistance in older adults, as measured by HOMA-IR
Reduced Harmful Effects of Oxidative Stress:
The ability of NAC + Glycine to improve glutathione status and reduce oxidative stress without inducing reductive stress is a key advantage over other antioxidant supplementation strategies
A study from the Baylor College of Medicine suggests that the use of NAC + Glycine supplementation as a promising strategy for promoting healthy aging and improving multiple age-related health outcomes.
By addressing key hallmarks of aging, such as glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, and physical decline, NAC + Glycine supplementation may help to prevent or mitigate various age-related diseases and extend healthspan.
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Beyond digestive benefits, BPC-157 supports new cell proliferation, contributing to the body's ongoing renewal processes. This means it is able to accelerate the body's healing process, specifically around soft tissue injuries. Studies have shown that BPC-157 can promote the healing of muscles, tendons, and ligaments by enhancing fibroblast activity (necessary for new tissue formation) and reducing scarring of the muscle. By increasing regeneration speed of these tissues and reducing scarring, it's possible to significantly improve the recovery process. BPC-157 has also been studied for its positive impact on conditions such as rheumatoid arthritis, osteoarthritis, and osteoporosis.
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Resources :1. Perovic, D., Vukojevic, J., & Zemba Cilic, M. (2019). BPC 157 resolves neuronal damage and prevents memory, locomotor, and coordination deficits. Neurotherapeutics, 17(4), 1990-1995. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504390/2. Lojo, N., Medvidovic-Grubisic, M., & Drmic, D. (2017). Gastric juice: a unique combination of hydrochloric acid. Journal of Gastroenterology and Hepatology, 35(2), 80-85. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928904/3. Chang, C. H., Tsai, W. C., & Pang, J. H. (2011). Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts. Tendon Research, 23(5), 374-380. https://pubmed.ncbi.nlm.nih.gov/21030672/4. Sikiric, P., Seiwerth, S., & Cesarec, V. (2017). Stable gastric pentadecapeptide BPC 157 is an anti-ulcer peptidergic. Peptides, 67, 14-18. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333585/5. Duzel, A., Vlainic, J., & Seiwerth, S. (2012). Stable gastric pentadecapeptide BPC 157 is an anti-ulcer peptidergic. International Journal of Pharmacology, 29(6), 121-126. https://pubmed.ncbi.nlm.nih.gov/22950504/
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Resources :1. Perovic, D., Vukojevic, J., & Zemba Cilic, M. (2019). BPC 157 resolves neuronal damage and prevents memory, locomotor, and coordination deficits. Neurotherapeutics, 17(4), 1990-1995. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8504390/2. Lojo, N., Medvidovic-Grubisic, M., & Drmic, D. (2017). Gastric juice: a unique combination of hydrochloric acid. Journal of Gastroenterology and Hepatology, 35(2), 80-85. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928904/3. Chang, C. H., Tsai, W. C., & Pang, J. H. (2011). Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts. Tendon Research, 23(5), 374-380. https://pubmed.ncbi.nlm.nih.gov/21030672/4. Sikiric, P., Seiwerth, S., & Cesarec, V. (2017). Stable gastric pentadecapeptide BPC 157 is an anti-ulcer peptidergic. Peptides, 67, 14-18. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333585/5. Duzel, A., Vlainic, J., & Seiwerth, S. (2012). Stable gastric pentadecapeptide BPC 157 is an anti-ulcer peptidergic. International Journal of Pharmacology, 29(6), 121-126. https://pubmed.ncbi.nlm.nih.gov/22950504/
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