Recent research has highlighted the potential benefits of NAC + Glycine, which combines N-acetylcysteine (NAC) and glycine, to include:
Restoration of Health Gluathione Levels:
Glutathione levels decline significantly with age, leading to increased oxidative stress and potentially contributing to various age-related health problems
Improved Mitochondrial Function:
NAC + Glycine supplementation has been shown to improve mitochondrial fatty acid oxidation and correct multiple aspects of mitochondrial dysfunction in older adults,
including abnormalities in mitochondrial biogenesis, nutrient sensing, β-oxidation, electron transport chain function, ATP synthesis, and mitophagy
Metabolic Health:
Aging is also associated with the development of insulin resistance and metabolic dysfunction. NAC + Glycine supplementation has been shown to significantly improve insulin sensitivity and reduce insulin resistance in older adults, as measured by HOMA-IR
Reduced Harmful Effects of Oxidative Stress:
The ability of NAC + Glycine to improve glutathione status and reduce oxidative stress without inducing reductive stress is a key advantage over other antioxidant supplementation strategies
In addition, a study from the Baylor College of Medicine suggests that the use of NAC + Glycine supplementation as a promising strategy for promoting healthy aging and improving multiple age-related health outcomes.
By addressing key hallmarks of aging, such as glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, and physical decline, NAC + Glycine supplementation may help to prevent or mitigate various age-related diseases and extend healthspan.