Staff: AMPk Activator

$16.94 USD

Staff: AMPk Activator

$16.94 USD
Benefits How To Use Key Ingredients FAQ Learn More

AMPk Activator - Created with GlucoVantage®

Our AMPk Activator formula, formerly "Dihydroberberine", features a highly bioavailable form of dihydroberberine: GlucoVantage®, which has been shown to be up to 5x more bioavailable and 2x longer lasting than regular berberine.

Dihydroberberine may help:

  • Maintain healthy blood glucose levels and improve insulin sensitivity*
  • Promote healthy cholesterol & lipid metabolism*
  • Support blood vessel health*
  • Reduce glycation end products, thought to contribute to biological aging*
  • Eliminate digestive upset that can occur with regular berberine*
  • May help increase plasma BHB ketones.*

Dihydroberberine is ideal for men and women who want an effective nutritional therapy for glucose balance, lipid metabolism and cardiovascular health that is both well-tolerated and convenient.* 


  • 60 count bottle/ 200mg each
  • Easy-to-swallow capsules
  • No salt, sugar, starch, artificial flavors, colors, sweeteners or preservatives
  • Gluten-free/Non-GMO
  • Vegan/Vegetarian
  • Keto Friendly
  • Free of common allergens (milk, egg, fish, shellfish, soy, peanuts, tree nuts and wheat)

Deeper Look:

Dihydroberberine is a metabolite of berberine which bypasses the rate-limiting step of microbial reduction, ensuring greater functional benefits over berberine. [7],[8] 

Berberine has been shown to directly interact with adenosine mono-phosphate kinase (AMPK), a protein that plays a key role in regulating energy balance.[2]

AMPK activity is felt in various bodily processes, including those relevant to insulin sensitivity. In fact, berberine has been shown to increase AMPK activity, which can enhance insulin sensitivity.[3]

Berberine supplementation has improved multiple markers of insulin sensitivity in research. Studies have found that the ingredient can lower blood glucose, hemoglobin, triglycerides, and cholesterol.[6]

Berberine increases adiponectin,[4] a protein secreted by fat cells that influences insulin reception on a cellular level. Further research has found that this increase in adiponectin improves insulin sensitivity. [5]

Results from pre-clinical studies indicate berberine promotes healthy endothelial function, an action attributed in part to its ability to reduce oxidative stress.[1]



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