This advanced brain-boosting formula combines nootropic compounds with paraxanthine, a naturally occurring caffeine metabolite that delivers clean energy without the jitters or crash. Paraxanthine also supports improved mood and provides neural protection by reducing oxidative stress. 7,8-Dihydroxyflavone (7,8-DHF) is included for its ability to cross the blood-brain barrier and mimic brain-derived neurotrophic factor (BDNF). This activation promotes neuroplasticity, enhances synaptic connectivity, and supports memory retention.
Paraxanthine:
The primary metabolite of caffeine—making up approximately 80% of caffeine metabolism in the body—Paraxanthine is largely responsible for the alertness and cognitive boost people associate with their morning coffee.
Blocks adenosine receptors more effectively than caffeine, leading to enhanced alertness, sustained wakefulness and mental clarity without excessive stimulation or jittery side effects.*
By increasing cGMP (cyclic guanosine monophosphate) levels in the brain’s striatum, paraxanthine supports better executive function, decision-making, cognitive flexibility, and faster response times.*
Enhances nitric oxide activity, which promotes vasodilation and increased blood flow to the brain, improving oxygen and nutrient delivery for optimal cognitive function.*
Unlike caffeine, paraxanthine does not metabolize into theophylline or theobromine, reducing the risk of jitters, headaches, and digestive issues.*
Possesses a longer half-life than caffeine, providing sustained focus and energy throughout the day with a lower likelihood of withdrawal symptoms.*
7,8 Dihydroxyflavone:
7,8-Dihydroxyflavone (7,8-DHF) is a naturally occurring flavone found in some plants. It is best known as a potent TrkB receptor agonist and ability to cross the blood brain barrier (BBB), mimicking brain-derived neurotrophic factor (BDNF)—a key player in neuroplasticity, synaptic function, and overall brain health.
Enhances neuroplasticity and memory by activating TrkB receptors; mimicking BDNF.*
Supports mood and stress resilience through BDNF activation, promoting synaptic remodeling and reducing feelings of depression and anxiety.*
Reduces neuroinflammation and oxidative stress due to antioxidant properties, reducing glutamate excitotoxicity and neuroinflammation.*
Neuroprotective against cognitive decline by protecting neurons from amyloid-beta toxicity and oxidative damage. Also helps maintain dopaminergic neurons, which may make it helpful in the prevention and/or treatment of neurogenerative diseases.
Lion’s Mane:
Contains bioactive compounds that can cross the blood brain barrier to stimulate nerve growth factors (NGFs), indirectly supporting TrkB activity and promoting the growth and repair of nerve cells.*
Boosts dopamine function, neurogenesis and synaptic plasticity improving cognitive function, memory, and focus.*
Helps reduce stress & promote a positive mindset by modulating serotonin and dopamine levels and supporting hippocampal regeneration.*
May improve energy and sleep balance, improving mitochondrial function, reducing sleep disturbances and supporting deep sleep without sedation.*
Enhances gut microbiome health and immune system function via modulation of macrophages, NK cells and T-cells.*
Bacopa:
Boosts brain-derived neurotropic factor (BDNF), increasing synaptic plasticity and long-term memory and offering improved attention and cognitive processing*
Acts as an adaptogen, helping to mitigate stress, regulate cortisol and boost neurotransmitters to promote a sense of well-being*
Antioxidant properties help protect the brain from oxidative stress and may support mitochondrial health. Promotes a healthy inflammatory response suppressing pro-inflammatory enzymes and cytokines*
Enhances brain detox during sleep by supporting glymphatic function, improves sleep quality including REM, dream recall, and deep sleep – without sedation*
Supports focus, attention span and reduces mental fatigue; helpful for students as well as professionals and may help reduce ADHD symptoms, such as restlessness and self-control*
Phosphatidylserine:
Improves cell-to-cell communication in the brain, and thus cognitive function, at least in part by increasing cell membrane fluidity.* Other mechanisms of action include enhancing cell metabolism (such as glucose utilization) and neurotransmitter formation.*
Possesses antioxidant properties, which would protect brain cells from free radicals.* Abundant clinical research has shown this nutrient is important in promoting optimal cognitive function, particularly in the aging brain.*
Studies show supplementing with phosphatidylserine can lower cortisol spikes in response to stress.* PS modulates cortisol by blunting the release of the hormone in the brain (ACTH) that normally signals the adrenal glands to secrete cortisol.*
Alpha-GPC:
Alpha-GPC is one of the most bioavailable forms of choline, which can enhance levels of acetylcholine, an important neurotransmitter in the brain.*
Increases acetylcholine levels, protecting neurons, enhancing synaptic plasticity, and potentially aiding in the treatment of cognitive disorders.*
Boosts neurotransmitter activity, increasing brain energy, supporting neuroplasticity, maintaining brain cell health, reducing cognitive decline, and enhancing memory and learning.*
Can enhance Growth Hormone production by stimulating the pituitary gland, supporting acetylcholine production, and potentially improving exercise performance and recovery.*
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